The Valentine Clinic, in Vancouver Washington, offers three different versions of neuromodulators or wrinkle relaxers: Botox Dysport and Xeomin.

How much does Botox treatment cost?

Botox, Xeomin, and Dysport are priced per unit of active ingredient. Botox is $11-$12/unit, Letybo is $10-$11/unit and Dysport is $4/unit depending on the number of units.

Savings are often available for patients receiving multiple treatments (PDO threads/Filler/RF Microneedling/Laser/Aquafirme) at the same appointment.

How Botox or Wrinkle Relaxers Work

Wrinkle relaxers are injected into the facial muscles to relax the muscles to improve the appearance of fine lines and wrinkles. Neuromodulators like Botox and Xeomin work to treat dynamic wrinkles.

Dynamic and Static Wrinkles

There is a distinction between dynamic wrinkles and static wrinkles. Dynamic wrinkles are visible on the face during muscular contractions, such as frowning and squinting. Once these muscles relax, dynamic wrinkles disappear as the skin springs back to its original position. However, over time, these dynamic wrinkles become creases in the skin, even at rest.

Common dynamic wrinkles include:

• Frown lines between eyebrows

• Forehead wrinkles

• Crow’s feet

• Smile lines around the mouth

Wrinkle relaxers, like Botox, Dysport, and Letybo, are an effective treatment for dynamic wrinkles as they temporarily and partially relax facial muscles. As dynamic wrinkles fade when the underlying muscle contractions are relaxed, these dynamic wrinkles begin to smooth out, leading to a youthful, refreshed look.

On the other hand, static wrinkles are visible even when facial muscles are relaxed. As we age, the production of collagen declines, causing the skin to lose its elasticity. As a result, dynamic wrinkles eventually become static wrinkles. Neuromodulators like Botox, Dysport, and Letybo effectively prevent dynamic wrinkles in the forehead and smile lines around the eyes and mouth. However, they are not as effective for treating static wrinkles. Instead, microneedling with radiofrequency, injectable dermal fillers, and PDO threads are best for addressing static wrinkles.

FAQs

How are they different?

Botox, Dysport and Letybo all work to relax wrinkles by temporarily reducing muscle contractions in the face. Each product also contains the same active ingredient: botulinum toxin A.

They differ in the added proteins of each product. Botox uses a protein to stabilize the active ingredient. Dysport uses a slightly smaller protein and Letbyo is the newest FDA approved neuromodulator. Letybo provides comparable results with Botox and Dysport with a focus on natural movement and expression. It’s an excellent option for clients seeking a fresh, modern alternative to traditional neurotoxins.

Onset of Action

Dysport and Letybo tend to have a faster onset than Botox and Xeomin, usually within 2 or 3 days.

Spread

Dysport spreads more easily and quickly than Botox and Letybo because of the smaller protein. This can be both positive and negative depending on how large the treatment area is.

Duration

Botox and Letybo tends to last longer than Dysport depending on how each provider mixes Dysport. The Dysport at The Valentine Clinic is a strong mix, so duration will often be as good or better than Botox and similar to Letybo.

Resistance

Letybo may have a lower risk of the body developing resistance to it, especially since it is the newest on the market. We recommend trying each neuromodulator—Botox, Dysport, and Letybo—as our patients often benefit from periodically rotating products for optimal results.

Are there any side effects?

Side effects of wrinkle relaxers are rare. The most common side effect is a transient headache post injections. Temporary swelling and/or bruising can occur. There is also a risk of eyebrow or eyelid ptosis. However, this is a very rare complication in the hands of an experienced injector.

When will I start seeing results?

Results can be seen as early as 2-3 days post treatment, but full results can take up to 14 days. Results typically last 3 months but may last longer with higher doses in the hands of an experienced injector.

What else can wrinkle relaxers be used for?

Cosmetically, they can be used to lift and shape the brow, remove furrows, lift the tip of the nose, lift the drooping edges of the mouth, tighten and slim jaw line, soften neck circular lines, soften neck vertical lines and get rid of “gummy” smiles. It can also effectively reduce migraines, TMJ pain and more.

How long is an appointment?

• 10 minutes for established patient

• 30 minutes for new patient